Real World Bleeding Risk Of Aspirin In Primary Prevention Examined
by Forbes on June 6, 2012
A new study published in JAMA provides substantial new evidence about the real world effects of aspirin, including the risk of bleeding, in a broad population. The study also sheds important new light on the effects of aspirin in a diabetic population.
Giorgia De Berardis and colleagues analyzed data from more than 4 million people in Puglia, Italy and compared 186,425 people taking low-dose aspirin with the same number of matched controls not taking aspirin.
Major bleeding events requiring hospitalization:
aspirin: 5.58 (5.39-5.77) per 1000 person-years
controls: 3.60 ( 3.48-3.72) per 1000 person-years
Incidence rate ratio (IRR) 1.55 (1.48-1.63)
Diabetics overall had an increased risk of major bleeding episodes but this increased risk was not significantly associated with aspirin use:Read More
Can Aspirin Help Ward Off Skin Cancer?
by TIME on May 29, 2012
An aspirin a day could keep skin cancer away, according to a new report in the journal Cancer.
Researchers in Denmark and the U.S. found that people taking common painkillers like aspirin and ibuprofen were less likely to develop skin cancer — including squamous cell carcinoma and malignant melanoma — especially when they took the drugs for at least seven years or used them at least twice a week. It’s not the first study to show a potential anticancer effect of aspirin and other similar painkillers — a class of medications known and nonsteroidal anti-inflammatory drugs, or NSAIDs. Previous studies have found that aspirin users enjoyed a lower risk of colon cancer; a trial published earlier this year concluded that people who take a daily aspirin have as much as a 46% lower risk of colon, lung and prostate cancers, compared with non-users. Read More
Does aspirin fight bowel cancer?
by Ballymena Times on May 7, 2012
The risk of dying from bowel cancer can be “slashed by taking an aspirin a day”, according to the Daily Mirror.
The news is based on a large Dutch study that examined the medical records of bowel cancer patients to see whether they had used aspirin before and after diagnosis. It found that those who used aspirin frequently after their diagnosis had a 33% greater chance of surviving for at least nine months than patients who had not been prescribed the drug or who only used the drug infrequently after diagnosis. The association between aspirin and improved survival rates was strongest in elderly patients who were not having chemotherapy. Read More
Next Big Thing: Aspirin to Cut Cancer Risk
by MedPage Today on April 10, 2012
Recent evidence suggests it will not be long before low-dose aspirin is included in recommendations for preventing cancer, researchers argued.
Even a 10% reduction in the rate of all cancers within the first 10 years of treatment could make the risk-benefit ratio favorable to aspirin in people with average risk, according to Michael Thun, MD, of the American Cancer Society in Atlanta, and colleagues. Read More
Aspirin ‘Cuts Cancer Death Risk By 30%’
by Sky News on April 25, 2012
Taking aspirin daily after being diagnosed with bowel cancer can reduce the chances of dying by almost a third, research has shown.
Patients who took the painkiller for at least nine months after diagnosis cut the risk by 30%.
The study in the Netherlands also found that those who took it for any length of time after being diagnosed reduced the odds by 23% compared with not taking it at all.
Tests were carried out on 4,500 bowel cancer patients diagnosed between 1998 and 2007. Read More
Closer to using aspirin for cancer prevention
by CNN Health on April 10, 2012
A new report in the journal Nature Reviews Clinical Oncology suggests that we could be inching closer to using aspirin as part of clinical guidelines in cancer prevention.
The U.S. Preventive Services Task Force encourages an aspirin regimen for some patients to prevent heart problems and strokes.
Aspirin has also been shown to reduce the risk of colorectal cancer and colorectal polyps. Although taking aspirin daily has some promising benefits, it can also raise the risk of gastrointestinal bleeding. Read More
Studies Link Daily Doses of Aspirin to Reduced Risk of Cancer
by The New York Times on March 20, 2012
Taking aspirin every day may significantly reduce the risk of many cancers and prevent tumors from spreading, according to two new studies published on Tuesday.
The findings add to a body of evidence suggesting that cheap and widely available aspirin may be a powerful if overlooked weapon in the battle against cancer. But the research also poses difficult questions for doctors and public health officials, as regular doses of aspirin can cause gastrointestinal bleeding and other side effects. Past studies have suggested that the drawbacks of daily use may outweigh the benefits, particularly in healthy patients. Read More